The present invention relates to a transcutaneous drug delivery system and its method of production. The system comprises a transcutaneously administrable photosensitive therapeutically active agent, preferably a photosensitive non-steroidal antiinflammatory agent, such as ketoprofen; a gelling agent; a hydrophilic solvent; and a cosmetically acceptable particulate titanium dioxide. The constituents of the system and its production method are selected in a way that maximizes delivery of and intradermal levels of intact active agent.