Cinnamon protein active compounds can be used to treat, prevent and inhibit enzyme protein mediated diseases caused by cinnamon protein. These compounds may help treat type 2 diabetes, hyperglycemia, metabolic syndrome, obesity, high cholesterol and high blood pressure.Or a pharmaceutically acceptable salt, wherein: t is selected from the following groups:N and N-oxides； u are selected from the following groups:N and N-oxides； V are selected from the following groups:N and N-oxides； W are selected from the following groups:N and N-oxides, provided that at least one T, u, and W is n or N-oxide； X from: - ch8322 -.- Shh...-CF8322-,- yes.- that is...-O-Ch832222---O-CH₂CH₂-,- en...-C (O) --NHC (O) -,-C (o) NH--NHSO832222---I meanY-CO832220-a. Each ch832222 is not replaced or replaced by one or two substitutes selected from hydrofluorocarbons, halogens, nh832222；1. Lease land No. c833218331 and 832626；CO₂H, CO₂-C₁₋₆ alkyl,CO-C₁₋₆ alkyl,a. Phenyl y-ch832222-phenyl, in which each NH is not replaced or replaced by a selected substitute:CO₂H, CO₂-C₁₋₆ alkyl,CO-C₁₋₆ alkyl,1. Phenyl y-ch832222-phenyl； and selected from other formulas (2)；a. 1, 2, 3, 4 or 5 alternatives selected from r74955 have not been replaced or replaced；Z from: No. 83099；- yes.Besides, it isEach R1 and R2 is independently selected: hydrogen, halogen, CN, cf83323；-Apartment 83318326, No. c832183,-C₂₋₆ alkenyl,-C₂₋₆ alkynyl,- (CH) -cicloalquilo C- (CH₂) ₚ-C₃₋₇-aryl cycloalkyl, - (CH₂) ₚ-C₃₋₇-heteroaryl cycloalkyl, - (CH₂) ₚ-C₄₋₁₀ -cycloalkenyl,- (CH₂) ₚ-C₄₋₇-aryl cycloalkenyl, - (CH₂) ₚ-C₄₋₇-heteroaryl cycloalkenyl, - (CH₂) ₚ-C₂₋₁₀ -cycloheteroalkyl,- (CH) -cicloheteroalquenilo C- (CH) -arilo - (CH) -aril-alquilo C- (CH) -aril-alquenilo C- (CH₂) ₚ-aryl-C₂₋₈-alkynyl-C₁₋₈ alkyl,- (CH₂) ₚ-aryl-C₂₋₈ alkynyl-C₃₋₇ cycloalkyl,- (CH₂) ₚ-aryl-C₂₋₈-alkynyl-C₃₋₇-cycloalkenyl,- (CH) -aril-alquinil C -cicloheteroalquilo C- (CH) -aril-alquinil C -cicloheteroalquenilo C- (CH₂) ₚ-aryl-C₂₋₈-alkynyl-aryl, - (CH₂) ₚ-aryl-C₂₋₈-
