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COMPOSITIONS AND METHODS FOR TREATING CANCER WITH A COMBINATION OF AN ANTAGONIST OF PD-1 AND AN ANTI-CTLA4 ANTIBODY
专利权人:
Merck Sharp &; Dohme Corp.
发明人:
Blanca Homet Moreno,Nageatte Ibrahim,Scot W. Ebbinghaus,Lokesh Jain,Scott Diede
申请号:
US16499674
公开号:
US20200115451A1
申请日:
2018.03.28
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention relates to method for treating cancer comprising administering an antagonist of PD-1, e.g., anti-PD-1 antibody or antigen binding fragment thereof, and an anti-CTLA4 antibody or antigen binding fragment thereof, wherein the CTLA4 antibody or antigen binding fragment thereof is given at a fixed dose. Also provided are compositions and kits comprising a dosage of an anti-PD-1 antibody and a dosage of an anti-CTLA4 antibody, and uses thereof.
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