Calitor Sciences, LLC;Sunshine Lake Pharma Co., Ltd.
发明人:
Ning Xi,Yanjun Wu,Min Liao,Yanming Feng
申请号：
US13945925
公开号：
US08969388B1
申请日:
2013.07.19
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention provides novel substituted pyrazolone compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.
