YU HA NA,BAIK HYE JUNG,YANG WON KYU,KO JIN YOUNG,JUNG SUNG BUM,AN SUNG WON,KI MIN HYO
申请号:
IN1082/KOLNP/2015
公开号:
IN2015KN01082A
申请日:
2015.04.20
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
Disclosed is a sustained release lipid pre concentrate comprising: a) at least one liquid crystal former b) at least one neutral phospholipid c) at least one liquid crystal hardener and d) at least one anionic anchoring agent wherein the sustained release pre concentrate exists as a lipid liquid phase in the absence of aqueous fluid and forms into a liquid crystal upon exposure to aqueous fluid. The sustained release lipid pre concentrate is configured to enhance the sustained release of cationic pharmacologically active substance through ionic interaction between the anionic anchoring agent and the cationic pharmacologically active substance.