David M. Hoganson;Jeffrey T. Borenstein;Joseph P. Vacanti
发明人:
David M. Hoganson,Joseph P. Vacanti,Jeffrey T. Borenstein
申请号：
US15440888
公开号：
US10670585B2
申请日:
2017.02.23
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention provides an in vitro blood vessel model for investigation of drug induced vascular injury and other vascular pathologies. The in vitro blood vessel model provides two channels separated by a porous membrane that is coated on one side by an endothelial cell layer and is coated on the other side by a smooth muscle cell layer, wherein said model is susceptible to the extravasation of red blood cells across said porous membrane due to drug induced vascular injury.
