Compound of formula I: wherein R1 is selected from the group consisting of: - H, alkyl, alkynyl, aryl, alkoxy, heterocyclyl and heteroaryl, wherein the alkyl, alkynyl, aryl, alkoxy, heterocyclyl or heteroaryl may be substituted Prompter optionally with one substituents selected from the group consisting of: -H, -OH, halogen, -CON (R4) 2, -N (R4) 2, -CO-C1-10 alkyl, -CO-O-alkyl C1-10, -N 3, aryl and heterocyclyl, each selected from the group consisting of -H R4independientemente, C1-10 alkyl, C1-10 -alkyl-aryl or aryl, a is C1-C6 alkyl, B is - N (R2) (R3), R2 is - (CO) -R5, R5 is selected from the group consisting of: alkyl, including groups of straight and branched chain and cyclic groups, alkynyl, aryl, yheteroarilo heterocyclyl, each of which may be unsubstituted or substituted with one or more substituents seleccionadosde from the group consisting of -H, -OH, halogen, -CN, -NO2, -COOH, -SH, -CO-alk Uilo C1-6, -CO-O-C1-6alkyl, -N 3, aryl, heterocyclyl, -CO-aryl or -CO-heterocyclyl, R3 is selected from the group consisting of: alkenyl, heteroaryl, cycloalkyl and heterocyclyl, wherein alkenyl, heteroaryl, cycloalkyl or heterocyclyl can be unsubstituted or substituted conuno or more substituents selected from the group consisting of -H, alkyl, alkenyl, alkoxy, halogen, -OH, -N 3, trifluoromethyl, -alkyl- aryl, -O-alkyl-aryl, -CO-aryl, aryl, heterocyclyl, heteroaryl, -CO-heteroaryl, -CO-O-, -CO-N-alkyl, -CO-N-aryl, or solvates, salts, N oxides or stereoisomers, pharmaceutically acceptable or combinacionesde thereof thereof.Compuesto de fórmula I: en la que R1 se selecciona de entre el grupo que consiste en: - H, alquilo, alquinilo, arilo, alcoxi, heterociclilo y heteroarilo,en el que alquilo, alquinilo, arilo, alcoxi, heterociclilo o heteroarilo puede sustituirse opcionalmente con uno omás sustituyentes seleccionados de entre el grupo que consiste en: -H, -OH, halógeno, -CON(R4)2, -N(R4)2, -CO-alquilo C1-10, -CO-O-alquilo C1-10, -N3, arilo y heterociclilo, siendo cada
