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METHOD FOR MANUFACTURING NATURAL KILLER T (NKT) CELL - STIMULATING DENDRITIC CELL, METHOD FOR MANUFACTURING CELL COMPOSITION CONTAINING THE NKT CELL STIMULATING DENDRITIC CELL AND NKT CELL, AND CELL COMPOSITION CONTAINING THEREOF
专利权人:
Riken Immune Regenerative Medicine Inc.
发明人:
Katsuo NOGUCHI,Toshio TADAKI
申请号:
US16329858
公开号:
US20190241871A1
申请日:
2017.08.31
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Provided is a method for manufacturing NKT-cell stimulating dendritic cells, the method including: a step for placing mononuclear cells in a culturing vessel and allowing some of the mononuclear cells to settle on a bottom surface of the vessel by keeping the culture still; a step for removing floating cells other than the cells that have settled on the bottom surface of the culturing vessel; a step for causing monocytes among the cells that have settled on the bottom surface to differentiate into immature dendritic cells by adding a predetermined factor to the culturing vessel; and a step for inducing mature dendritic cells into NKT-cell stimulating dendritic cells by adding α-galactosylceramide to the culturing vessel.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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