Compositions and methods for treating defects in avascular cartilaginous tissue by directly administering one or more metabolites of simvastatin

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专利权人:

University of Cincinnati

发明人:

Lin, Chia-Ying James

申请号：

AU2018269008

公开号：

AU2018269008A1

申请日:

2018.05.15

申请国别(地区):

AU

年份:

2019

代理人:

摘要：

Controlled release hydrogel formulations of one or more simvastatin metabolites 3'-hydroxy simvastatin (hSV), 6'-exomethylene simvastatin (eSV), 3',5'-dihydrodiol simvastatin, 3', 5'-dihydrodiol simvastatin (dSV), simvastatin-beta-hydroxy acid (SVA), and methods for the treatment of patients suffering from injured or degenerating substantially avascular cartilaginous tissue.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/