Nigel H. Greig,Karen T. Y. Shaw,Qiang-Sheng Yu,Harold W. Holloway,Tada Utsuki,Timothy T. Soncrant,Donald K. Ingram,Arnold Brossi,Anthony Giordano,Gordon Powers,Diane M. Davidson,Michael Sturgess
申请号:
US12841888
公开号:
US08258172B2
申请日:
2010.07.22
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides compounds and methods of administering compounds to a subject that can reduce βAPP production and that is not toxic in a wide range of dosages. The present invention also provides non-carbamate compounds and methods of administering such compounds to a subject that can reduce βAPP production and that is not toxic in a wide range of dosages. It has been discovered that either the racemic or enantiomerically pure non-carbamate compounds can be used to decrease βAPP production.