Robert MACLAREN,Alun R. BARNARD,Samantha R. DE SILVA,Mark W. HANKINS
申请号:
US16119587
公开号:
US20180360912A1
申请日:
2018.08.31
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A method of treating an eye disease comprising administering an adeno-associated virus (AAV) vector to a mammalian subject by subretinal injection, wherein the AAV vector comprises a nucleotide sequence encoding melanopsin operably linked to an expression control sequence to promote expression of melanopsin in cells of the eye of the subject.