#$%^&*AU2018200758A120180222.pdf#####ABSTRACT The present invention relates to mutations in Epidermal Growth Factor Receptor (EGFR) and methods of detecting such mutations as well as prognostic methods for identifying tumors that are 5 susceptible to anticancer therapy such as chemotherapy and/or kinase inhibitor treatment. The methods involve determining the presence of a mutated (EGFR) gene or mutated (EGFR) protein in a tumor sample whereby the presence of a mutated (EGFR) gene or protein indicates the tumor is susceptible to treatment. 9934831_1 (GHMatters) P71002.AU.4