The presently disclosed subject matter is directed generally to monolayer or multilayer films suitable for use in forming pouches, such as (but not limited to) medical solution pouches. When used in the formation of solution pouches, the disclosed films help prevent or reduce the presence of bubbles in the solution after heat sterilization, such as autoclaving. In particular, the presently disclosed subject matter provides a polymeric film for forming pouches that are capable of passing the bubble test as set forth in the Chinese State Drug Package Container Material Standard No. YBB00112005. The disclosed film comprises at least one anti-foaming layer comprising copolyether-ester copolymer.
