The present invention provides methods, compositions, and systems for preventing or reducing an allergic condition in an offspring by administering tocopherol to a mother pregnant or nursing the offspring, where the tocopherol in the composition is 98-100% unmodified natural d-alpha tocopherol, and less than 2% gamma tocopherol (e.g., undetectable levels of gamma tocopherol). In certain embodiments, a prenatal tablet or pill is provided composed of such tocopherol compositions in combination with folic acid, iron, and calcium.