Xin LI,Binqiang FENG,Yang CHEN,Tao LIU,Feng HE,Mingxun HE,Weikang TAO,Piaoyang SUN
申请号：
US15766985
公开号：
US20180297988A1
申请日:
2016.09.30
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention relates to an oxa spiro derivative, a preparation method therefor, and applications thereof in medicines. Particularly, the present invention relates to an oxa spiro derivative represented by formula (I), a preparation method therefor, and a pharmaceutical composition comprising the derivative, applications thereof as an MOR receptor agonist, and applications in the preparation of drugs for treating and/or preventing pains and pains-related diseases. Substituent groups in the formula (I) are same as definitions in the specification.
