THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM;THE MEDICAL COLLEGE OF WISCONSIN
发明人:
IMIG JOHN DAVID,CAMPBELL WILLIAM B.,FALCK JOHN RUSSELL
申请号:
NZ61740212
公开号:
NZ617402A
申请日:
2012.04.04
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Disclosed are compounds which are analogs of epoxyeicosatrienoic acid (EET) for example 1-(11-(2-hydroxyphenylthio)undec-5(Z)-enyl)-3-n-pentylurea and compositions containing these compounds. The compounds act as EET agonists and are intended for use as medications in the treatment of drug-induced nephrotoxicity, hypertension and other related conditions. Also disclosed are methods of making and using the compounds and compositions comprising the compounds.