THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA
发明人:
HAY, MEREDITH,BARNES, CAROL,KONHILAS, JOHN
申请号:
CA2916701
公开号:
CA2916701A1
申请日:
2014.06.30
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
The present invention provides compositions and methods for treating cognitive impairment or dysfunction in a subject. In particular, the present invention provides a method for using a composition comprising an angiotensin-(l-7) receptor agonist to treat cognitive dysfunction or impairment that is due to a various clinical conditions including, but not limited to, those associated with increase in inflammation, cytokine production, increases in reactive oxygen species, changes in expression of brain inflammatory related genes and/or in the expression of genes involved in learning and memory within the central nervous system of a subject.