Devices and methods for modular mandibular prostheses. The prosthesis includes a plurality of connector links that can be connected together in a desired size and orientation. For example, a ball and socket may provide the ability to configure to most 3D configuration. Each link has a body with engagement structures on first and/or second ends of the body. The engagement structure on the first end of a first link may be received by the engagement structure on the second end of a second link. The connected links can be in a locked and unlocked state. An expansion or compression member engages the connected link to cause the prosthesis to be in the locked state. An end attachment may be used on ends of outermost connected links to attach the prosthesis to a patient's mandible.