Майкл О'Нил Ханрахан,Ричард Л.,Дастин,Майкл ОНил Ханрахан
申请号:
EA201790234
公开号:
EA201790234A1
申请日:
2015.08.19
申请国别(地区):
EA
年份:
2017
代理人:
摘要:
Formulations, methods and substituted 2'-chloraminopyrimidinone and pyrimidinedione compounds of formula (I) are proposed for the treatment of infection caused by the Pneumovirinae virus subfamily, including infections caused by a respiratory syncytial virus, as well as methods and intermediate compounds for the synthesis of substituted 2'-chloroimopyrimidinidine and idioprotein and idioprotein type viruses and the intermediate compounds for the synthesis of substituted 2'-chloroimopyrimidinone viruses and the intermediate compounds for the synthesis of the substituted 2'-chloroimine pyridine syncytial virus, as well as methods and intermediates for the synthesis of the substituted 2'-chloroimine pyridine syncytial virus, as well as methods and intermediate compounds compounds.Предложены составы, способы и замещенные 2'-хлораминопиримидиноновые и пиримидиндионовые соединения формулы (I) для лечения инфекции, вызванной вирусом подсемейства Pneumovirinae, включая инфекции, вызванные респираторно-синцитиальным вирусом, а также способы и промежуточные соединения для синтеза замещенных 2'-хлораминопиримидиноновых и пиримидиндионовых соединений.