The present invention provides methods compositions and kits for treating intestinal hyperpermeability in a subject in need thereof including conditions such as hyperglycemia and underlying diseases such as diabetes autism fibromyalgia inflammatory bowel disease (IBD) graft versus host disease (GVHD) HIV/ AIDS multiple organ dysfunction syndrome irritable bowel syndrome (IBS) celiac disease eczema psoriasis acute pancreatitis Parkinson s disease depression chronic fatigue syndrome asthma multiple sclerosis arthritis ankylosing spondylitis nonalcoholic fatty liver disease alcoholic cirrhosis environmental enteropathy or kwashiorkor.
