ANNAPURNA PENDRI,BRADLEY C. PEARCE,CHRISTOPHER W. CIANCI,DAVID R. LANGLEY,GUO LI,SAMUEL GERRITZ,SEAN KIM,SHIRONG ZHU,SHUHAO SHI,WEIXU ZHAI
申请号：
BR112013007651
公开号：
BR112013007651A2
申请日:
2011.09.23
申请国别(地区):
BR
年份:
2019
代理人:
摘要：
A compound of Formula I is set forth, including pharmaceutically acceptable salts thereof: wherein Het is a 5 or 6-membered heterocycle with &mdash；N, &mdash；O, or &mdash；S adjacent to the &mdash；Ar substituent or adjacent to the point of attachment for the &mdash；Ar substituent； Ar is aryl or heteroaryl； R is &mdash；CH3, &mdash；CH2F, &mdash；CHF2 or &mdash；CH&boxH；CH2； V is &mdash；H, &mdash；CH3 or &boxH；O； W is &mdash；NO2, &mdash；Cl, &mdash；Br, &mdash；CH2OH, or &mdash；CN； X is &mdash；Cl, &mdash；Br, &mdash；F, &mdash；CH3, &mdash；OCH3, or &mdash；CN； Y is &mdash；CH or &mdash；N； and Z is &mdash；CH or &mdash；N. This compound is useful in compositions for the prevention and treatment of influenza virus.
