compound, pharmaceutical composition and its uses and methods for treating secondary hypogonadism or associated disorder, infertility in women, type 2 diabetes in male humans, breast cancer in women and endometrial, ovarian or uterine cancer in women, to prevent the transition from metabolic syndrome to type 2 diabetes in male human and breast cancer in female and to reduce fasting blood glucose levels in male human
The present invention relates to substantially pure metabolites of irara-clomiphene. The invention is also directed to pharmaceutical compositions comprising these metabolites and their use in treating disorders including secondary hypogonadism, type 2 diabetes, elevated cholesterol, elevated triglycerides, wasting, lipodystrophy, female and male infertility, benign prostate hypertrophy, prostate cancer, breast cancer, ovarian cancer and endometrial cancer.