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A method of treating a malignancy in a subject and a pharmaceutical composition for use in same
专利权人:
Viralytics Limited
发明人:
Shafren, Darren R.
申请号:
AU2015230743
公开号:
AU2015230743A1
申请日:
2015.09.23
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
#$%^&*AU2015230743A120151015.pdf#####A METHOD OF TREATING A MALIGNANCY IN A SUBJECT AND A PHARMACEUTICAL COMPOSITION FOR USE IN SAME ABSTRACT There is disclosed a method of killing abnormal cells such as malignant cells including melanoma cells, using a virus recognising at least one of a cell adhesion molecule and a complement regulatory protein. The virus may be a member of the Picornaviridae family. Coxsackie A-group viruses have been found to be particularly suitable. The cell adhesion molecule is desirably a member of the immunoglobulin (Ig) superfamily. Typically, the complement regulatory protein will be DAF.
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