MACDONALD, Lynn,MURPHY, Andrew,MCWHIRTER, John,TU, Naxin,VORONINA, Vera,GURER, Cagan,MEAGHER, Karolina,STEVENS, Sean
申请号:
LT20120784833T
公开号:
LT2771357(T)
申请日:
2012.10.26
申请国别(地区):
立陶宛
年份:
2018
代理人:
摘要:
The invention provides a genetically modified non-human animal that comprises in its genome unrearranged T cell receptor variable gene loci, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified non-human animal and methods of making the same. Various methods of using the genetically modified non-human animal are also provided.