Emory University;Children's Healthcare of Atlanta, Inc.
发明人:
Jacques Galipeau,Hsiang-Chuan Hsieh
申请号：
US16007392
公开号：
US20180289799A1
申请日:
2018.06.13
申请国别(地区):
US
年份:
2018
代理人:
摘要：
In certain embodiments, this disclosure relates to conjugates comprising GM-CSF and IL-7 and uses related thereto, e.g., enhancing the adaptive immune system. Typically the GM-CSF and IL-7 are connected by a polymer linker, e.g., polypeptide. In certain embodiments, the disclosure relates to nucleic acids encoding these polypeptide conjugates, vectors comprising nucleic acid encoding polypeptide conjugates, and protein expression systems comprising these vectors such as infectious viral particles and host cells comprising such a nucleic acids.
