The device and method of blood oxygenation are disclosed. The equipment includes that multiple passive mixing elements one cause fluid that can mix as it flows through the device. The part oxygen interflow road that passive mixing elements continuously expose new red blood cell wherein occurs. Therefore, in some embodiments, which uses less hemoperfusion units, and the oxygenation of blood is allowed to have a large amount of short flow channels, when with traditional oxygenation method and device.
