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Use of Cannabidiol in the Treatment of Hepatitis
专利权人:
Mitzi Nagarkatti;Prakash S. Nagarkatti
发明人:
Prakash S. Nagarkatti,Mitzi Nagarkatti
申请号:
US13562750
公开号:
US20120302646A1
申请日:
2012.07.31
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Cannabinoids are known to interact with CB1 and CB2 receptors expressed in the nervous and immune systems mediating a wide range of effects, including anti-inflammatory properties. However, cannabinoids that bind CB1 are also psychoactive thereby limiting their clinical use. Cannabidiol (CBD) is the most abundant nonpsychotropic plant cannabinoid but has not been studied as extensively as Δ9-tetrahydrocannabinol (THC). The present disclosure reports the immunosuppressive properties of CBD and demonstrates that CBD induces apoptosis in thymocytes and splenocytes and inhibits the proliferative responsiveness of T and B cells. This indicates that CB2 selective agonists, devoid of psychotropic effect, may serve as novel anti-inflammatory/immunosuppressive agents.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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