An endoscopic imaging system (100) includes an endoscope (120), a light source assembly (125) coupled to the endoscope that transmits light to the endoscope for illuminating a region of interest, an imaging unit (130) coupled to the light source assembly that receives light through the endoscope reflected from the region of interest, a first power module coupled to the light source assembly that provides electrical power to the light source assembly, and a second and different power module coupled to the imaging unit that provides electrical power to the imaging unit. Other imaging systems and a method are also disclosed.