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USE OF COMPLEMENT PATHWAY INHIBITORS TO TREAT OCULAR DISEASES
专利权人:
GENENTECH; INC.
发明人:
FUNG, SEK, CHUNG,YAO, ZHENGBIN
申请号:
PH12013501270
公开号:
PH12013501270A1
申请日:
2013.06.17
申请国别(地区):
PH
年份:
2016
代理人:
摘要:
The present invention relates to the treatment of ocular diseases and conditions by administering a complement pathway inhibitor, particularly an alternative pathway inhibitor. Ocular diseases include age-related macular degeneration, diabetic retinopathy, and ocular angiogenesis. One embodiment comprises the administration of an anti-Factor D antibody in the form of a whole antibody, a Fab fragment or a single domain antibody. Other complement component inhibitors that may be useful in the present method include Factor H or inhibitors that block the action of properdin, factor B, factor Ba, factor Bb, C2, C2a, C3a, C5, C5a, C5b, C6, C7, C8, C9, or C5b-9.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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