Brian K. Roberts,Gopal Chandra Saha,Brian Edward Lavan,Charles A. McWherter
申请号:
US14667145
公开号:
US09439891B2
申请日:
2015.03.24
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed herein are pharmaceutical compositions, methods and kits for lowering the serum uric acid level of a subject and for the treatment of a condition associated with elevated serum uric acid levels comprising administering a composition comprising a first urate-lowering agent and a second urate-lowering agent. In some aspects the first urate-lowering agent is (−)-halofenate, (−)-halofenic acid, or a pharmaceutically acceptable salts thereof. In some aspects the second urate-lowering agent is an inhibitor of uric acid production, a uricosuric agent, a uricase, or a pharmaceutically acceptable salt thereof.