The invention relates to a fluid-connection device (10) capable of and intended for connecting a flexible pipe (11) defining a first fluid space (71) to a second flexible pipe (11) or a flexible fluid enclosure (12) in a biopharmaceutical assembly, including a first connector (1) and a second connector (1 2) which is equivalent to the first connector, the first connector and the second connector being capable of and intended for coupling together in an asexual manner, according to an insertion movement which essentially involves axial translation along the axis A into a relative coupling position, which defines a mating surface (P), each connector including, alternately in a circumferential direction, N flexible snap-fitting tabs (6) and N halting surfaces (8), the flexible snap-fitting tabs projecting axially forward relative to the mating surface, and the halting surfaces (8) being arranged set back from the mating surface, such that when in coupling position, the snap-fitting tabs of one of the connectors snap-fit with the halting surfaces of the other one of the connectors, such that the position thus obtained is locked by the snap-fitting tabs.Dispositif de connexion fluidique (10) apte et destiné à raccorder un tube souple (11) délimitant un premier espace fluidique (71) à un deuxième tube souple (11) ou une enceinte souple fluide (12),dans un ensemble biopharmaceutique, comprenant un premier connecteur (1), un deuxième connecteur (12), analogue au premier connecteur, le premier connecteur et le second connecteur étant aptes et destinés à venir se coupler mutuellement de manière asexuée, selon un mouvement dinsertion essentiellement de translation axiale selon laxe A, jusque dans une position de couplage relative, laquelle définit un plan de joint (P), chacun connecteurs comprenant, de façon alternée selon une direction circonférentielle, N pattes (6) de clipsage flexibles et N surfaces darrêt (8), les pattes de clipsage flexible faisant saillie axialement ver