3-substituted 1,3,4-oxadiazole compounds and thiadiazole as immunomodulators

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专利权人:

AURIGENE DISCOVERY TECHNOLOGIES LIMITED

发明人:

APPUKKUTTAN PRASAD,MURALIDHARA RAMACHANDRA,POTTAYIL GOVINDAN NAIR SASIKUMAR,SEETHARAMAIAH SETTY SUDARSHAN NAREMADDEPALLI

申请号：

BR112017019307

公开号：

BR112017019307A2

申请日:

2016.03.10

申请国别(地区):

BR

年份:

2018

代理人:

摘要：

The present invention relates to 3-substituted 1,3,4-oxadiazole and thiadiazole compounds of formula (I) and their use to inhibit programmed cell death signaling pathway 1 (pd-1) and / or to treat of disorders inhibiting an immunosuppressive signal induced by pd-1, pd-11 or pd-12.a presente invenção se refere a compostos de 1,3,4-oxadiazol 3-substituído e tiadiazol de fórmula (i) e seu uso para inibir a via de sinalização de morte celular programada 1 (pd-1) e/ou para o tratamento de distúrbios inibindo um sinal imunossupressor induzido por pd-1, pd-l1 ou pd-l2.

来源网站：

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