Described herein is the Bruton’s tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one, including crystalline forms, solvates and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions that include the Btk inhibitor, as well as methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.此處描述布魯頓氏酪胺酸激酶(Btk)抑制劑1-((R)-3-(4-胺基-3-(4-苯氧基苯基)-1H-吡唑并[3,4-d]嘧啶-1-基)哌啶-1-基)丙-2-烯-1-酮，包括其結晶型、溶劑合物及藥學上可接受之鹽類。也揭示含括該Btk抑制劑之藥學組成物，以及使用該Btk抑制劑單獨使用或組合其它治療劑用以治療自體免疫病或病況、異種免疫病或病況、癌症包括淋巴瘤、及發炎病或病況之方法。
