METHOD FOR PREPARING ROSUVASTATIN CALCIUM INTERMEDIATE

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专利权人:

Porton Fine Chemicals Ltd.

发明人:

Wenqing LIN,Hongjie ZHENG,Peng YANG

申请号：

US13757846

公开号：

US20130143908A1

申请日:

2013.02.03

申请国别(地区):

US

年份:

2013

代理人:

摘要：

A method for preparing a rosuvastatin calcium intermediate represented by formula I. The method includes: hydrolyzing an ester compound represented by formula II (in which, R represents C1-C5) in the presence of a metal compound to obtain a carboxylic acid compound represented by formula III and reducing the carboxylic acid compound in the presence of a reductant.

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