Christopher F. Claiborne,Stephen Critchley,Steven P. Langston,Hirotake Mizutani,Edward J. Olhava,Stephane Peluso,Stepan Vyskocil,Gabriel S. Weatherhead
申请号:
US14827556
公开号:
US09458108B2
申请日:
2015.08.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
This invention relates to compounds that inhibit E1 activating enzymes, pharmaceutical compositions comprising the compounds, and methods of using the compounds. The compounds are useful for treating disorders, particularly cell proliferation disorders, including cancers, inflammatory and neurodegenerative disorders and inflammation associated with infection and cachexia.