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DÉRIVÉ DE THIOPYRIDINE, ET COMPOSITION PHARMACEUTIQUE LE CONTENANT ET AYANT UNE ACTION ANTI-HELICOBACTER PYLORI
专利权人:
aRigen Pharmaceuticals; Inc.
发明人:
申请号:
EP10761444.8
公开号:
EP2420500A1
申请日:
2010.04.08
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Disclosed are a novel pyridine thio derivative, and a pharmaceutical composition using the novel pyridine thio derivative, particularly a pharmaceutical composition having selective antibacterial activity against Helicobacter pylori. Specifically disclosed is a pyridine thio derivative represented by general formula (I) (wherein R1 and R2 each represents a hydrogen atom, a C1-8 alkyl group or the like; R3 and R4 each represents a hydrogen atom, a C1-8 alkyl group or the like; X represents -O-, -S- or the like; Y represents a C1-12 alkyl group which may be substituted by a substituent or -(RS-O)n-R6(wherein R5 represents a C1-5 alkylene group; R6 represents a C1-8 alkyl group which may be substituted by a substituent, and n represents an integer of 1-10); and Z represents a hydrogen atom or the like), or a pharmacologically acceptable salt thereof. Also specifically disclosed is a pharmaceutical composition containing the pyridine thio derivative or a salt thereof.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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