The present invention provides computer-implemented methods and systems for monitoring and informing a user about known side effects of drugs (e.g., prescription, over-the-counter) using a wearable device, the method including: polling for sensor data from a wearable device； the sensor data indicating one or more vital signs measurement parameters of a user, wherein the sensor data is used for evaluating whether one or more known side effects has been detected； transmitting a request for information to various networks, the information request including identification of at least one drug the user is using； receiving the requested information from the various networks for monitoring and detecting one or more known side effects of the identified drug； storing the received information from the various networks into memory of the wearable device； evaluating, for each identified drug, the obtained sensor data with the stored information received from the various networks pertaining to that identified drug； determining whether one or more known side effects have been detected, wherein the determination is based on the evaluation of the sensor data with the stored information about the identified drug； executing one or more actions to notify the user and other third parties based on the detected one or more known side effects； and executing an algorithm to adjust the drug delivery regime responsive to the determination that one or more known side effects have been detected.
