The current invention discloses a system for detecting an intraoral disease and determining a personalized treatment scheme; the system comprising: a. a reservoir configured for accommodating a sample of a biologic material collected in an oral cavity of a patient; b. a first detector for detecting a first substance originating from bacteria; c. a second detector for detecting a second substance originating from at least one of an immune and an inflammatory system of the patient; d. a control unit configured for operatively receiving signals from the first and second detectors and analyzing the signals; and e. display and communication means configured for presenting results of signal analysis; wherein the control unit is configured for determining said treatment scheme comprising relevant antimicrobial compositions and a dosing frequency thereof. Additionally, the present invention recommends customized cannabis-based oral care products.