The invention described herein provides for human antibodies produced in non-humananimals that specifically bind to lipopolysaccharide (LPS) from strains FisherDevlin (International Serogroups) It-2 (011), It-3 (02), It-4 (01), It-5 (010),It-6 (07), PA01 (05), 170003 (02), IATS016 (02/05), and 170006 (02). The inventionfurther provides methods for making the antibodies in a non-human animal, expressionof the antibodies in cell lines including hybridomas and recombinant host cellsystems. Also provided are kits and pharmaceutical compositions comprisingthe antibodies and methods of treating or preventing pseudomonas infectionby administering to a patient the pharmaceutical compositions described herein.
