A spinal screw fixation device is provided. The spinal screw fixation device includes a spinal screw, a fixing screw, and a locking plate. The spinal screw has an oblique perforation hole through which the fixing screw passes. The locking plate has two locking holes through which the spinal screw and the fixing screw pass, respectively. The spinal screw, the fixing screw and the locking plate constitute a three-point fixed structure.