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3. HIV protein inhibitors
专利权人:
INC.;GILEAD SCIENCES
发明人:
XU, LIANHONG,XU, JIE,YANG, HONG,VOIGT, JOHANNES,QI, YINGMEI,MFADDEN, RYAN,JABRI, SALMAN Y.,HAN, XIAOCHUN,GONZALEZ BUENROSTRO, ANA ZURISADAI,CHO, AESOP,CAI, ZHENHONG R.
申请号:
ARP180102964
公开号:
AR113765A1
申请日:
2018.10.12
申请国别(地区):
AR
年份:
2020
代理人:
摘要:
1. Claim 1: a formula compound (1),N is 0-2; m is 0-1; R 1 is selected from the group consisting of hydrogen, halogen, cyanogen and hydrocarbon group c832283331;-Or7491,Isomerization of 5-10 members, isomerization of 3-12 members, arilo of 5-10 members and cyclopentadiene of 3-10 members, c832283331 of each asphalt;Isomerization of 5 to 10 members, isomerization of 3 to 12 members, Ariel of 6 to 10 members and ring of 3 to 10 members can be replaced by 1 to 5 r830404;2. Each R2 is selected independently of the group composed of hydrogen and c83218832626;-No. 7491; No. 74955;Halogen, cyanogen and - or74919,a. Option to replace lease No. c83218sp31832626 with one to five r83042 units;O r 1 and R 2, together with their attached atoms, form a selective heteromorphism, which is replaced by 83040 groups at 1 to 5 ℃;The value of R3 ° is c833217c831832626;a. C832283316o cycloquilo of 3 to 10 persons could be replaced by 1 to 5 r83040 groups;R830808 was selected from the group consisting of - C (o) r74919;-C(O)Or7491,-C (o) No. 7491; (r7495); and;-OC(O)NR7491;R7495;-No. 7491; (C (o) r7495;-No. 7491; (C (o) No. 74959;-S(o)8320318322;R74919;-S(O)8322;-7491;-R74955;-No. 7491; (s (o) 8322; r74955;-No. 7491; (s (o) 832183318322; or74955;-OS(O)832118°833122;NR7491;R7495Y-Or74919;R83099 was selected from a panel consisting of 5 to 10 members of cyanide, halides and heteromaterials, in which the 5 to 10 members of the group could be replaced by 1 to 5 r83044;R8310 is hydrogen, halogen, cyanogen and halogen c83218338323;-C (o) No. 7491; (r7495); and;O change the option from 5 to 10 members to 1 to 5 r83040;Each r831181 shall be independent of the group listed in lease agreement No. c8332188331832626;Alcoxi C832188331636262;-No. 7491; No. 74955;a. Halogen, cyanogen, 5-10 members of arilo, 3-6 members of cyclopentadiene, 5-10 members of heterogeneity and 3-12 members of non cyclopentadiene, each tar c832183318383226;Alcoxi C832188331636262;a. Arilo with 5-10 members, cyclopropene with
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