Donald W. Landry,Yuli Xie,Yidong Liu,Gangli Gong,Shi-Xian Deng,Kirsten Alison Rinderspacher
申请号：
US13178117
公开号：
US20120029022A1
申请日:
2011.07.07
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension.
