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PROCOAGULANT PEPTIDES, THEIR DERIVATIVES AND THEIR APPLICATION
专利权人:
ЭТИКОН; ИНК. (US)
发明人:
ВАН И-Лан (US),ЧЖАН Гуанхой (US)
申请号:
RU2014102975/15
公开号:
RU2014102975A
申请日:
2012.06.14
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A hemostatic material or tissue healing material, comprising: (a) a peptide having the sequence of SEQ ID NO: 1 or its sequence of amino acid analogues, and (b) a framework. The hemostatic material or tissue healing material according to claim 1, wherein said framework is a natural or genetically engineered absorbable polymer, a synthetic absorbable polymer, or combinations thereof. The hemostatic material or tissue healing material according to claim 2, wherein said natural or genetically engineered absorbable polymer is selected from the group consisting of protein, polysaccharide, and combinations thereof. The hemostatic material or tissue healing material according to claim 3, wherein said protein is selected from the group consisting of prothrombin, thrombin, fibrinogen, fibrin, fibronectin, heparinase, factor X / Xa, factor VII / VIIa, factor IX / IXa, factor XI / XIa, factor XII / XIIa, tissue factor, batroxobin, ancrod, ecarin, von Willebrand factor, collagen, elastin, albumin, gelatin, platelet surface glycoproteins, vasopressin, analogues of vasopressin, epinephrine, selectin, procoagulant inhibitor, agen platelet activating peptides and their combinations. 5. The hemostatic material or tissue healing material according to claim 3, wherein said polysaccharide is selected from the group consisting of cellulose, alkyl cellulose, methyl cellulose, alkyl hydroxyalkyl cellulose, hydroxyalkyl cellulose, cellulose sulfate, carboxymethyl cellulose salts, carboxymethyl cellulose, carboxyethylethyl, acid carboxyethyl hyaluronic acid1. Гемостатический материал или материал для заживления тканей, содержащий:(a) пептид, имеющий последовательность SEQ ID NO: 1 или его последовательность аналогов аминокислот, и(b) каркас.2. Гемостатический материал или материал для заживления тканей по п.1, в котором упомянутый каркас представляет собой натуральный или генно-инженерный абсорбируемый полимер, синтетический абсорбируемый полимер или их комбинации.3. Гемостатический мате
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