A physiological sensing method and a device using the same is disclosed. The two sides of the device are respectively provided with an installed component. The device is arranged on the wrist of a user through the installed components. At least two physiological sensors, arranged in row on the installed component, generate and transmit original physiological signals to a controller. The controller filters out the original physiological signals to generate two basic energy values, multiplies the two basic physiological parameters by the two basic energy values to generate two basic estimation parameters, and substitutes the two basic energy values into a standard physiological value equation to generate a standard physiological value.