LOOZEN, HUBERT JAN JOZEF,EDERVEEN, ANTONIUS GERARDUS HENDRIKUS,DIJCKS, FREDERICUS ANTONIUS
申请号:
CA2577497
公开号:
CA2577497C
申请日:
2005.09.05
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention provides 15.beta.-substituted steroidal compounds havingselective estrogen receptor activity according to Formula (I) wherein, R1 isH, C1-5 alkyl, C1-12 acyl, di-(C1-5 alkyl)aminocarbonyl, (C1-5alkyl)oxycarbonyl or sulfamoyl, R2 is H, C1-3alkyl, C2-3alkenyl or C2-3alkynyl, each of which may be optionally substituted with a halogen, R3 is C1-2alkyl, ethenyl or ethynyl, each of which may be optionally substituted with ahalogen, and R4 is H or C1-12 acyl.