Fusion protein containing antifreeze protein and human epidermal growth factor with enhanced antioxidant function and skin cell proliferation effect, and cosmetic composition for wrinkle improvement containing the same as active ingredients
The present invention relates to a fusion protein of antifreeze protein and human epidermal growth factor having an increased antioxidant function and skin cell proliferation effect and a cosmetic composition for wrinkle improvement containing the same as an active ingredient. The fusion protein of the invention is useful as a raw material for functional cosmetics having excellent antioxidant activity, high skin cell proliferation effect, and excellent skin regeneration effects such as skin wrinkle improvement and whitening.本発明は、抗酸化機能及び皮膚細胞増殖効果が増大した不凍タンパク質とヒト上皮細胞成長因子との融合タンパク質並びにそれを有効成分として含有するしわ改善用化粧料組成物に関するものであって、本発明の融合タンパク質は、抗酸化活性に優れ、かつ皮膚細胞増殖効果が高く、皮膚しわ改善、美白などの皮膚再生効果に優れた機能性化粧料の原料として有用である。