The present invention relates to a vesicle derived from Catenibacterium bacteria and a use thereof. The present inventors have confirmed experimentally that the vesicles were significantly reduced in samples of patients with malignant diseases such as colorectal cancer, pancreatic cancer, cholangiocarcinoma, ovarian cancer, bladder cancer, and lymphoma, cardiovascular diseases such as myocardial infarction, atrial fibrillation, variant angina, and stroke, diabetes, Parkinson's disease, and depression compared to a normal person, and the vesicles inhibited secretion of an inflammatory mediator by pathogenic vesicles such as E. coli-derived vesicles. Therefore, the vesicles derived from Catenibacterium bacteria according to the present invention may be effectively used for developing a diagnostic method for malignant diseases such as colorectal cancer, pancreatic cancer, cholangiocarcinoma, ovarian cancer, bladder cancer, and lymphoma, cardiovascular diseases such as myocardial infarction, atrial fibrillation, variant angina, and stroke, diabetes, Parkinson's disease, and depression, and for developing a composition for preventing or treating the above-mentioned diseases.La présente invention concerne une vésicule dérivée de bactéries Catenibacterium et une utilisation associée. Les présents inventeurs ont confirmé expérimentalement des teneurs significativement réduites des vésicules dans des échantillons de patients atteints de maladies malignes telles que le cancer colorectal, le cancer du pancréas, le cholangiocarcinome, le cancer de l'ovaire, le cancer de la vessie et le lymphome, de maladies cardiovasculaires telles que l'infarctus du myocarde, la fibrillation auriculaire, l'angine de Prinzmetal, et l'accident vasculaire cérébral, le diabète, la maladie de Parkinson et la dépression par comparaison à une personne normale, et que les vésicules inhibent la sécrétion d'un médiateur inflammatoire par des vésicules pathogènes telles que des vésicules dérivées de E. c
