Michael Härter,Hartmut Beck,Susanne Greschat-Schade,Peter Ellinghaus,Kerstin Unterschemmann,Joachim Schuhmacher
申请号:
US13696878
公开号:
US20130172311A1
申请日:
2011.05.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present application relates to novel substituted 1-[3-(heterocyclyl)benzyl]-1H-pyrazole derivatives, to processes for preparation thereof, to use thereof for treatment and/or prevention of diseases and to use thereof for production of medicaments for treatment and/or prevention of diseases, more particularly for treatment and/or prevention of hyperproliferative and angiogenic diseases and those diseases which arise from metabolic adaptation to hypoxic states. Such treatments can be effected in the form of monotherapy or else in combination with other medicaments or further therapeutic measures.