The present invention refers to a composition comprising human albumin at a concentration between 5% (w/v) and 25% (w/v) for the treatment of mild and moderate Alzheimer’s Disease (AD) by low-volume plasma exchange (LVPE).本發明係關於一種包含濃度在5%(w/v)與25%(w/v)之間的人類白蛋白的組合物用於藉由低容量血漿置換(LVPE)來治療輕度及中度阿茲海默氏症(Alzheimer’s Disease;AD)。