TAKAISHI, MAMORU,SATO, NOBUHIRO,SHIBUGUCHI, TOMOYUKI,MOTOKI, TAKAFUMI,TAKAHASHI, YOSHINORI,SASAKI, TAKEO,BRAUNTON, ALAN
申请号:
EP14756740
公开号:
EP2963043A4
申请日:
2014.02.26
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
A compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof works as an mGluR2 antagonist, and is applicable as a therapeutic agent for neurological disorders related to glutamate dysfunction and diseases involving the mGluR2, such as Alzheimer's disease: wherein R is a hydrogen atom, a C 1-6 alkyl group or the like, R 1 is a C 1-6 alkyl group, a C 1-6 alkoxy group or the like, R 2 is a halogen atom, a C 1-6 alkyl group, a C 1-6 alkoxy group or the like, R 3 is a hydrogen atom, a C 1-6 alkyl group or the like, and R 4 is a C 1-6 alkyl group or the like.